Laboratory Products
New CRISPR-Cas9 Cell Lines for Target Identification, Validation and Pathway Discovery
Feb 25 2020
Abcam’s new CRISPR-Cas9 knockout (KO) cell lines provide reproducible, single gene KOs that support the interrogation of the relationship between genotype and phenotype.
Obtaining high-quality KO cell lines and lysates that match specific experimental requirements can be technically challenging and time consuming, requiring months for transfection, clone isolation and screening work. Having a reliable, ready-to-use source of KO cell lines allows researchers to confidently progress target identification and validation without the need to first establish a KO cell line.
Abcam’s newly launched collection provides the global scientific community with a wide range of KOs in commonly used immortalised cancer cell lines such as Hela and HEK293T. With an ever-expanding range of new targets and parental cell lines, selection and ordering is as easy as buying a reagent.
All KO cell lines are Sanger sequenced to confirm knockout, and many have additional Western blot data included. A wild-type positive control cell line is also available.
Abcam’s KO cell lines deliver: immediate access to pre-validated CRISPR-Cas9-engineered KO cell lines derived from Hela and HEK293T; supports target identification, validation and pathway discovery, antibody screening and validation, compound hit identification and validation as well as disease model development; no in-house CRISPR-Cas9 or molecular biology expertise required, saving >3 months of KO production work.
More information online
Digital Edition
Lab Asia 31.2 April 2024
April 2024
In This Edition Chromatography Articles - Approaches to troubleshooting an SPE method for the analysis of oligonucleotides (pt i) - High-precision liquid flow processes demand full fluidic c...
View all digital editions
Events
May 21 2024 Lagos, Nigeria
May 22 2024 Basel, Switzerland
Scientific Laboratory Show & Conference 2024
May 22 2024 Nottingham, UK
May 23 2024 Beijing, China
May 28 2024 Tel Aviv, Israel